Not with the files saved from GW-BASIC though, unless you add the extra A parameter to save as ASCII. I learned that recently when setting up a repo to experiment with GW-BASIC 1.0 (unlike the later Microsoft BASICs the original GW-BASIC is open source).
Annoying when saving the BAS files as ASCII they are still written as full blocks of some size 512 bytes?) with a ctrl-Z EOF to mark the end of the file. So there is some random binary garbage at the end of the file to strip away before committing changes. I wonder how common it was for DOS software to do that and how much sensitive information can be found at the end of released files if you look after the EOF marker?